HCG

HCG in Laboratory Research

HCG (human chorionic gonadotropin) is a glycoprotein hormone built from two non-covalently associated subunits: an alpha chain common to LH, FSH and TSH, and a hormone-specific beta chain that determines its receptor selectivity. Its high affinity for the luteinizing-hormone/chorionic-gonadotropin (LH/CG) receptor makes it a standard reference ligand in gonadotropin research.

Laboratories keep it on hand as a well-characterised agonist when a defined LH/CG-receptor ligand is needed under controlled laboratory conditions.

Research Applications & Study Focus

Studies using HCG concentrate on LH/CG-receptor binding and signalling, gonadal steroidogenesis, and comparative glycoprotein-hormone pharmacology. It is commonly applied in Leydig- and granulosa-cell models, cAMP second-messenger assays, and receptor-binding panels that characterise agonist potency and downstream response.

Reproducible lot specification supports consistent assay conditions across repeated steroidogenesis and receptor-pharmacology experiments.

Purity, Handling & Verification

Each batch is supplied as a sealed, lyophilized vial and is independently analysed by a third-party laboratory using HPLC and mass spectrometry; the full certificate of analysis is published against its lot number, so results can be verified before use. Store the lyophilized material cool, dry and out of direct light, and reconstitute with bacteriostatic water under standard aseptic laboratory practice.

This material is offered strictly for in vitro laboratory research use only. It is not for human or veterinary consumption, and not for diagnostic or therapeutic use.